(Download) "Treatment of Advanced Oropharyngeal Cancers with Chemotherapy and Radiation. (Original Article)." by Nose and Throat Journal Ear * eBook PDF Kindle ePub Free
eBook details
- Title: Treatment of Advanced Oropharyngeal Cancers with Chemotherapy and Radiation. (Original Article).
- Author : Nose and Throat Journal Ear
- Release Date : January 01, 2003
- Genre: Health & Fitness,Books,Health, Mind & Body,
- Pages : * pages
- Size : 202 KB
Description
Abstract We conducted a retrospective chart review of treatment outcomes in 17 adults who had been selected to undergo concomitant chemotherapy and radiation (chemo/XRT) for late-stage oropharyngeal cancers. All patients had been treated at the West Los Angeles VA Medical Center between March 1, 1998, and Sept. 30, 2000. Nine patients had a primary tumor at the base of the tongue, five had a primary tumor in the tonsillar area, and three had a tumor that affected both sites. Of this group, 15 patients completed one to three cycles of chemo/XRT, and the remaining two died during therapy. At the most recent follow-up, 9 of the 17 patients (52.9%) were documented to still be alive; seven patients had earlier died as a result of their primary tumor or a distant metastasis, and one patient had been lost to follow-up after completing treatment. At study 'send, the duration of post-treatment survival ranged from 2 to 36 months (mean: 12.5). Based on the results of our small series, we conclude that chemo/XRT is a valid alter native to surgery with postoperative radiation and to radiation alone. Chemo/XRT yields acceptable rates of local control and allows for organ preservation with tolerable side effects.
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